Childhood maltreatment and adult suicidality: a comprehensive systematic review with meta-analysis.
Psychol Med
; 49(7): 1057-1078, 2019 05.
Article
in En
| MEDLINE
| ID: mdl-30608046
ABSTRACT
This comprehensive systematic review and meta-analysis aims to quantify the association between different types of childhood maltreatment and suicidality. We searched five bibliographic databases, including Medline, PsychINFO, Embase, Web of Science and CINAHL, until January 2018. Random-effects meta-analysis was employed followed by univariable and multivariable meta-regressions. Heterogeneity was quantified using the I2 statistic and formal publication bias tests were undertaken. The methodological quality of the studies was critically appraised and accounted in the meta-regression analyses. Data from 68 studies based on n = 261.660 adults were pooled. All different types of childhood maltreatment including sexual abuse [odds ratio (OR) 3.17, 95% confidence interval (CI) 2.76-3.64], physical abuse (OR 2.52, 95% CI 2.09-3.04) and emotional abuse (OR 2.49, 95% CI 1.64-3.77) were associated with two- to three-fold increased risk for suicide attempts. Similar results were found for the association between childhood maltreatment and suicidal ideation. Complex childhood abuse was associated with a particularly high risk for suicide attempts in adults (OR 5.18, 95% CI 2.52-10.63). Variations across the studies in terms of demographic and clinical characteristics of the participants and other core methodological factors did not affect the findings of the main analyses. We conclude that there is solid evidence that childhood maltreatment is associated with increased odds for suicidality in adults. The main outstanding challenge is to better understand the mechanisms which underpin the development of suicidality in people exposed to childhood maltreatment because current evidence is scarce.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Suicide
/
Child Abuse, Sexual
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Child Abuse
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Suicidal Ideation
/
Adverse Childhood Experiences
Type of study:
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
/
Systematic_reviews
Limits:
Adolescent
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Adult
/
Child
/
Female
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Humans
/
Male
/
Middle aged
Language:
En
Journal:
Psychol Med
Year:
2019
Document type:
Article
Affiliation country:
United kingdom