Review of primary and secondary erythromelalgia.

Mann, N; King, T; Murphy, R

Mann, N; King, T; Murphy, R.

Affiliation

Mann N; Department of Dermatology, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.
King T; Department of Dermatology, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.
Murphy R; Department of Dermatology, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK.

Clin Exp Dermatol ; 44(5): 477-482, 2019 Jul.

Article in En | MEDLINE | ID: mdl-30609105

ABSTRACT

ABSTRACT

Erythromelalgia is a condition characterized by episodic pain, erythema and temperature of the extremities, which is relieved by cooling and aggravated by warming. It is useful to review this topic in light of recent discoveries of the genetic mutations that now define primary erythromelalgia, as opposed to secondary erythromelalgia, which is often associated with underlying medical disorders.

Subject(s)

Erythromelalgia/diagnosis; Capsaicin/therapeutic use; Erythromelalgia/complications; Erythromelalgia/genetics; Erythromelalgia/therapy; Humans; Mass Screening; Mexiletine/therapeutic use; Myeloproliferative Disorders/complications; Myeloproliferative Disorders/diagnosis; NAV1.7 Voltage-Gated Sodium Channel/genetics; Ranolazine/therapeutic use; Sensory System Agents/therapeutic use; Sodium Channel Blockers/therapeutic use; Sympathectomy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythromelalgia Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: Clin Exp Dermatol Year: 2019 Document type: Article Affiliation country: United kingdom Publication country: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM

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