An alternative N-terminal fold of the intestine-specific annexin A13a induces dimerization and regulates membrane-binding.

McCulloch, Kathryn M; Yamakawa, Izumi; Shifrin, David A; McConnell, Russell E; Foegeding, Nora J; Singh, Prashant K; Mao, Suli; Tyska, Matthew J; Iverson, T M

McCulloch, Kathryn M; Yamakawa, Izumi; Shifrin, David A; McConnell, Russell E; Foegeding, Nora J; Singh, Prashant K; Mao, Suli; Tyska, Matthew J; Iverson, T M.

Affiliation

McCulloch KM; From the Departments of Pharmacology.
Yamakawa I; From the Departments of Pharmacology.
Shifrin DA; Cell and Developmental Biology, and.
McConnell RE; Cell and Developmental Biology, and.
Foegeding NJ; Cell and Developmental Biology, and.
Singh PK; From the Departments of Pharmacology.
Mao S; Cell and Developmental Biology, and.
Tyska MJ; Cell and Developmental Biology, and.
Iverson TM; From the Departments of Pharmacology, tina.iverson@vanderbilt.edu.

J Biol Chem ; 294(10): 3454-3463, 2019 03 08.

Article in En | MEDLINE | ID: mdl-30610115

Subject(s)

Annexins/chemistry; Annexins/metabolism; Cell Membrane/metabolism; Intestinal Mucosa/metabolism; Protein Multimerization; Animals; Epithelial Cells/cytology; Humans; Hydrogen-Ion Concentration; Intestines; Liposomes/metabolism; Mice; Models, Molecular; Organ Specificity; Protein Binding; Protein Conformation, alpha-Helical; Protein Structure, Quaternary; Protein Transport

Key words

annexin; calcium regulation; intestinal microvilli; membrane curvature; membrane fusion; oligomerization; protein folding; protein structure; structure-function

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Membrane / Annexins / Protein Multimerization / Intestinal Mucosa Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2019 Document type: Article Country of publication: United States

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