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Novel small molecule IL-6 inhibitor suppresses autoreactive Th17 development and promotes Treg development.
Aqel, S I; Kraus, E E; Jena, N; Kumari, V; Granitto, M C; Mao, L; Farinas, M F; Zhao, E Y; Perottino, G; Pei, W; Lovett-Racke, A E; Racke, M K; Fuchs, J R; Li, C; Yang, Y.
Affiliation
  • Aqel SI; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Kraus EE; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Jena N; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Kumari V; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
  • Granitto MC; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
  • Mao L; Neuroscience Program, College of Arts and Sciences, The Ohio State University, Columbus, OH, USA.
  • Farinas MF; Department of Medicinal Chemistry, University of Florida, Gainsville, FL, USA.
  • Zhao EY; Neuroscience Program, College of Arts and Sciences, The Ohio State University, Columbus, OH, USA.
  • Perottino G; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Pei W; Neuroscience Program, College of Arts and Sciences, The Ohio State University, Columbus, OH, USA.
  • Lovett-Racke AE; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Racke MK; Department of Microbial Infection and Immunity, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Fuchs JR; Department of Neurology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Li C; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH, USA.
  • Yang Y; Department of Medicinal Chemistry, University of Florida, Gainsville, FL, USA.
Clin Exp Immunol ; 196(2): 215-225, 2019 05.
Article in En | MEDLINE | ID: mdl-30615197
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-6 / T-Lymphocytes, Regulatory / Small Molecule Libraries / Th17 Cells Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Exp Immunol Year: 2019 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interleukin-6 / T-Lymphocytes, Regulatory / Small Molecule Libraries / Th17 Cells Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Exp Immunol Year: 2019 Document type: Article Affiliation country: United States Country of publication: United kingdom