Formylation of Eukaryotic Cytoplasmic Proteins: Linking Stress to Degradation.
Trends Biochem Sci
; 44(3): 181-183, 2019 03.
Article
in En
| MEDLINE
| ID: mdl-30661830
ABSTRACT
Unlike prokaryotes, N-terminal formylation has been confined to a handful of mitochondrial proteins in eukaryotes. A recent study unveils a new role for eukaryotic cytoplasmic N-terminal formylation linking diverse cellular stresses to N-terminal-dependent protein degradation. These findings suggest broad cellular implications in higher eukaryotes for N-terminal methionine formylation.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Eukaryota
Language:
En
Journal:
Trends Biochem Sci
Year:
2019
Document type:
Article