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Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death.
Torossian, Avedis; Broin, Nicolas; Frentzel, Julie; Daugrois, Camille; Gandarillas, Sarah; Saati, Talal Al; Lamant, Laurence; Brousset, Pierre; Giuriato, Sylvie; Espinos, Estelle.
Affiliation
  • Torossian A; Inserm, UMR1037 CRCT, F-31000 Toulouse, France.
  • Broin N; Université Toulouse III-Paul Sabatier, UMR1037 CRCT, F-31000 Toulouse, France.
  • Frentzel J; CNRS, ERL5294 UMR1037 CRCT, F-31000, Toulouse, France.
  • Daugrois C; Inserm, UMR1037 CRCT, F-31000 Toulouse, France.
  • Gandarillas S; Université Toulouse III-Paul Sabatier, UMR1037 CRCT, F-31000 Toulouse, France.
  • Saati TA; CNRS, ERL5294 UMR1037 CRCT, F-31000, Toulouse, France.
  • Lamant L; Inserm, UMR1037 CRCT, F-31000 Toulouse, France.
  • Brousset P; Université Toulouse III-Paul Sabatier, UMR1037 CRCT, F-31000 Toulouse, France.
  • Giuriato S; CNRS, ERL5294 UMR1037 CRCT, F-31000, Toulouse, France.
  • Espinos E; Inserm, UMR1037 CRCT, F-31000 Toulouse, France.
Haematologica ; 104(7): 1428-1439, 2019 07.
Article in En | MEDLINE | ID: mdl-30679328

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Gene Expression Regulation, Neoplastic / Lymphoma, Large-Cell, Anaplastic / Proto-Oncogene Proteins c-bcl-2 / Crizotinib / Anaplastic Lymphoma Kinase / Antineoplastic Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Haematologica Year: 2019 Document type: Article Affiliation country: France Country of publication: Italy

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Gene Expression Regulation, Neoplastic / Lymphoma, Large-Cell, Anaplastic / Proto-Oncogene Proteins c-bcl-2 / Crizotinib / Anaplastic Lymphoma Kinase / Antineoplastic Agents Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Haematologica Year: 2019 Document type: Article Affiliation country: France Country of publication: Italy