Resveratrol promotes sensitization to Doxorubicin by inhibiting epithelial-mesenchymal transition and modulating SIRT1/ß-catenin signaling pathway in breast cancer.

Jin, Xiaoxia; Wei, Yingze; Liu, Yushan; Lu, Xiaoyun; Ding, Fei; Wang, Jiatai; Yang, Shuyun

Jin, Xiaoxia; Wei, Yingze; Liu, Yushan; Lu, Xiaoyun; Ding, Fei; Wang, Jiatai; Yang, Shuyun.

Affiliation

Jin X; Department of Pathology, Nantong Tumor Hospital, Nantong, China.
Wei Y; Department of Pathology, Nantong Tumor Hospital, Nantong, China.
Liu Y; Department of Pathology, Nantong Tumor Hospital, Nantong, China.
Lu X; Department of Pathology, Nantong Tumor Hospital, Nantong, China.
Ding F; Department of Pathology, Nantong Tumor Hospital, Nantong, China.
Wang J; Department of Pathology, Nantong Tumor Hospital, Nantong, China.
Yang S; Department of Pathology, Nantong Tumor Hospital, Nantong, China.

Cancer Med ; 8(3): 1246-1257, 2019 03.

Article in En | MEDLINE | ID: mdl-30697969

Subject(s)

Breast Neoplasms/metabolism; Breast Neoplasms/pathology; Doxorubicin/pharmacology; Epithelial-Mesenchymal Transition/drug effects; Resveratrol/pharmacology; Signal Transduction/drug effects; Sirtuin 1/metabolism; beta Catenin/metabolism; Apoptosis/drug effects; Breast Neoplasms/genetics; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; Cell Survival/drug effects; Drug Synergism; Female; Gene Expression; Humans; Sirtuin 1/genetics; beta Catenin/genetics

Key words

Doxorubicin; Drug resistance; EMT; SIRT1; breast cancer; resveratrol; ß-catenin

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Signal Transduction / Doxorubicin / Beta Catenin / Sirtuin 1 / Epithelial-Mesenchymal Transition / Resveratrol Limits: Female / Humans Language: En Journal: Cancer Med Year: 2019 Document type: Article Affiliation country: China Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google