Combined proteomic and miRNome analyses of mouse testis exposed to an endocrine disruptors chemicals mixture reveals altered toxicological pathways involved in male infertility.

Buñay, Julio; Larriba, Eduardo; Patiño-Garcia, Daniel; Urriola-Muñoz, Paulina; Moreno, Ricardo D; Del Mazo, Jesús

Buñay, Julio; Larriba, Eduardo; Patiño-Garcia, Daniel; Urriola-Muñoz, Paulina; Moreno, Ricardo D; Del Mazo, Jesús.

Affiliation

Buñay J; Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Catolica de Chile (PUC), Santiago, Chile.
Larriba E; Department of Cellular and Molecular Biology, Centro de Investigaciones Biologicas (CIB-CSIC), Madrid, Spain.
Patiño-Garcia D; Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Catolica de Chile (PUC), Santiago, Chile.
Urriola-Muñoz P; Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Catolica de Chile (PUC), Santiago, Chile.
Moreno RD; Chemistry Institute, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.
Del Mazo J; Department of Physiology, Faculty of Biological Sciences, Pontificia Universidad Catolica de Chile (PUC), Santiago, Chile.

Mol Hum Reprod ; 25(3): 156-169, 2019 03 01.

Article in En | MEDLINE | ID: mdl-30698749

Subject(s)

Endocrine Disruptors/toxicity; Infertility, Male/metabolism; MicroRNAs/metabolism; Proteomics/methods; Testis/drug effects; Testis/metabolism; Animals; Humans; Male; Mice

Key words

PGAM1; endocrine disruptors; infertility; isomiRs; miRNAs; proteome; spermatogenic failure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Testis / MicroRNAs / Proteomics / Endocrine Disruptors / Infertility, Male Limits: Animals / Humans / Male Language: En Journal: Mol Hum Reprod Journal subject: BIOLOGIA MOLECULAR / MEDICINA REPRODUTIVA Year: 2019 Document type: Article Affiliation country: Chile

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