Cu-ATCUN Derivatives of Sub5 Exhibit Enhanced Antimicrobial Activity via Multiple Modes of Action.

Alexander, Jessica L; Thompson, Zechariah; Yu, Zhen; Cowan, J A

Alexander, Jessica L; Thompson, Zechariah; Yu, Zhen; Cowan, J A.

Affiliation

Alexander JL; Evans Laboratory of Chemistry , The Ohio State University , 100 West 18th Avenue , Columbus , Ohio 43210 , United States.
Thompson Z; Evans Laboratory of Chemistry , The Ohio State University , 100 West 18th Avenue , Columbus , Ohio 43210 , United States.
Yu Z; Evans Laboratory of Chemistry , The Ohio State University , 100 West 18th Avenue , Columbus , Ohio 43210 , United States.
Cowan JA; Evans Laboratory of Chemistry , The Ohio State University , 100 West 18th Avenue , Columbus , Ohio 43210 , United States.

ACS Chem Biol ; 14(3): 449-458, 2019 03 15.

Article in En | MEDLINE | ID: mdl-30742402

Subject(s)

Antimicrobial Cationic Peptides/chemistry; Antimicrobial Cationic Peptides/pharmacology; Copper/chemistry; Nickel/chemistry; Amino Acid Motifs; Cell Line; Cell Membrane/metabolism; Cell Membrane Permeability; Cell Survival/drug effects; Drug Discovery/methods; Enterococcus faecium/drug effects; Escherichia coli/drug effects; Fibroblasts/cytology; Humans; Membrane Lipids/metabolism; Microbial Sensitivity Tests; Nucleic Acids/chemistry; Oxidation-Reduction; Protein Binding; Signal Transduction; Staphylococcus aureus/drug effects

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Copper / Antimicrobial Cationic Peptides / Nickel Limits: Humans Language: En Journal: ACS Chem Biol Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google