Vorinostat, a possible alternative to metronidazole for the treatment of amebiasis caused by Entamoeba histolytica.
J Biomol Struct Dyn
; 38(2): 597-603, 2020 02.
Article
in En
| MEDLINE
| ID: mdl-30744531
ABSTRACT
AbbreviationsSAHAsuberoylanilide hydroxamic acidEhHDACHistone Deacetylase from Entamoeba histolyticaRgRadius of gyrationRMSDroot-mean-square deviationRMSFroot-mean-square fluctuationMDSmolecular dynamics simulationVMDVisual Molecular DynamicsNAMDNanoscale Molecular DynamicsPBCperiodic boundary conditionsPMEParticle Mesh Ewald3Dthree-dimensionalCαalpha carbonFDAFood and Drug AdministrationnsnanosecondsGPU CUDAGraphics Processing Unit Compute Unified Device ArchitectureCommunicated by Ramaswamy H. Sarma.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Entamoeba histolytica
/
Amebiasis
/
Vorinostat
/
Metronidazole
Language:
En
Journal:
J Biomol Struct Dyn
Year:
2020
Document type:
Article