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Comparative study of urethroplasties to reduce urethral strictures in patients with severe hypospadias.
Huang, Li-Qu; Wang, Jun; Ge, Zheng; Ma, Geng; Lu, Ru-Gang; Deng, Yong-Ji; Huang, Song-Ming; Guo, Yun-Fei.
Affiliation
  • Huang LQ; 1 Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.
  • Wang J; 1 Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.
  • Ge Z; 1 Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.
  • Ma G; 1 Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.
  • Lu RG; 1 Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.
  • Deng YJ; 1 Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.
  • Huang SM; 2 Department of Nephrology, Children's Hospital of Nanjing Medical University, Nanjing, China.
  • Guo YF; 1 Department of Urology, Children's Hospital of Nanjing Medical University, Nanjing, China.
J Int Med Res ; 47(4): 1620-1627, 2019 Apr.
Article in En | MEDLINE | ID: mdl-30747026
ABSTRACT

OBJECTIVE:

Transverse island pedicle flap (TIPF) plus transected urethral plate-preserving urethroplasty is increasingly used for treatment of severe hypospadias. We aimed to reduce the occurrence of urethral strictures in patients undergoing such procedures.

METHODS:

Sixty-five patients with severe hypospadias were enrolled. Thirty-two patients underwent onlay-tube-onlay urethroplasty (Group A), and 33 patients underwent modified Duplay urethroplasty (Group B). Postoperative complications were recorded, including fistulas, urethral strictures, and diverticula.

RESULTS:

Three patients (9.4%) in Group A and 10 patients (30.3%) in group B had urethrocutaneous fistulas. Three patients (9.4%) in Group A and 0 patients (0%) in Group B had urethral strictures. No patient in the two groups had symptoms of diverticulum or penile chordee. The results of uroflowmetry were better in Group B than Group A, when comparing uroflow patterns.

CONCLUSIONS:

TIPF plus transected urethral plate-preserving urethroplasty can lower the occurrence of stricture, which is a challenging complication. The occurrence of stricture was lower in patients who underwent modified Duplay urethroplasty, and neourethral function and quality were better in these patient. Thus, this modified procedure can be used for treatment of severe hypospadias.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Urethra / Urethral Stricture / Plastic Surgery Procedures / Hypospadias Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Child, preschool / Humans / Male Language: En Journal: J Int Med Res Year: 2019 Document type: Article Affiliation country: China

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Postoperative Complications / Urethra / Urethral Stricture / Plastic Surgery Procedures / Hypospadias Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Child, preschool / Humans / Male Language: En Journal: J Int Med Res Year: 2019 Document type: Article Affiliation country: China