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Depletion of regulatory T cells in tumors with an anti-CD25 immunotoxin induces CD8 T cell-mediated systemic antitumor immunity.
Onda, Masanori; Kobayashi, Kazuto; Pastan, Ira.
Affiliation
  • Onda M; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; ondam@mail.nih.gov pastani@mail.nih.gov.
  • Kobayashi K; Department of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, 960-1295 Fukushima, Japan.
  • Pastan I; Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; ondam@mail.nih.gov pastani@mail.nih.gov.
Proc Natl Acad Sci U S A ; 116(10): 4575-4582, 2019 03 05.
Article in En | MEDLINE | ID: mdl-30760587
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunotoxins / T-Lymphocytes, Regulatory / CD8-Positive T-Lymphocytes / Interleukin-2 Receptor alpha Subunit / Immunotherapy / Antibodies, Monoclonal / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunotoxins / T-Lymphocytes, Regulatory / CD8-Positive T-Lymphocytes / Interleukin-2 Receptor alpha Subunit / Immunotherapy / Antibodies, Monoclonal / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Proc Natl Acad Sci U S A Year: 2019 Document type: Article Country of publication: United States