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AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells.
Nikolaou, Nikolaos; Gathercole, Laura L; Kirkwood, Lucy; Dunford, James E; Hughes, Beverly A; Gilligan, Lorna C; Oppermann, Udo; Penning, Trevor M; Arlt, Wiebke; Hodson, Leanne; Tomlinson, Jeremy W.
Affiliation
  • Nikolaou N; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK.
  • Gathercole LL; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK; Department of Biological and Medical Sciences, Oxford Brookes University, Oxford, OX3 0BP, UK.
  • Kirkwood L; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK.
  • Dunford JE; Botnar Research Institute, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7LD, UK.
  • Hughes BA; Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
  • Gilligan LC; Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
  • Oppermann U; Botnar Research Institute, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7LD, UK.
  • Penning TM; Department of Systems Pharmacology & Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, 1315 BRB II/III 421 Curie Blvd, Philadelphia, PA, 19104-6160, United States.
  • Arlt W; Institute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
  • Hodson L; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK.
  • Tomlinson JW; Oxford Centre for Diabetes, Endocrinology and Metabolism, NIHR Oxford Biomedical Research Centre, University of Oxford, Churchill Hospital, Oxford, OX3 7LE, UK. Electronic address: jeremy.tomlinson@ocdem.ox.ac.uk.
J Steroid Biochem Mol Biol ; 189: 218-227, 2019 05.
Article in En | MEDLINE | ID: mdl-30769091
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases / Receptors, Glucocorticoid / Carcinoma, Hepatocellular / Glucocorticoids / Liver Neoplasms Limits: Humans Language: En Journal: J Steroid Biochem Mol Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases / Receptors, Glucocorticoid / Carcinoma, Hepatocellular / Glucocorticoids / Liver Neoplasms Limits: Humans Language: En Journal: J Steroid Biochem Mol Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom