Benzophenone glycosides from the pericarps of Aquilaria yunnanensis S. C. Huang.
Nat Prod Res
; 34(14): 2030-2036, 2020 Jul.
Article
in En
| MEDLINE
| ID: mdl-30789078
ABSTRACT
Two new benzophenone glycosides, aquilarisides A (1) and B (2), together with six known analogues (3-8) were isolated from the pericarps of Aquilaria yunnanensis S. C. Huang. Their structures were elucidated on the basis of 1D and 2D NMR and mass spectroscopic analyses, and the absolute configuration of compound 1 was determined by experimental and calculated electronic circular dichroism (ECD) spectra. Anti-inflammatory activities of all compounds 1-8 were evaluated for their inhibitory activities against lipopolysaccharide (LPS)-stimulated induced nitric oxide (NO) production in RAW 264.7 cells using the Griess assay. Compound 2 indicated a weak inhibition of NO production.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Benzophenones
/
Thymelaeaceae
/
Glycosides
/
Anti-Inflammatory Agents
Limits:
Animals
Language:
En
Journal:
Nat Prod Res
Year:
2020
Document type:
Article