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Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent Clostridioides difficile infection.
Mullish, Benjamin H; McDonald, Julie A K; Pechlivanis, Alexandros; Allegretti, Jessica R; Kao, Dina; Barker, Grace F; Kapila, Diya; Petrof, Elaine O; Joyce, Susan A; Gahan, Cormac G M; Glegola-Madejska, Izabela; Williams, Horace R T; Holmes, Elaine; Clarke, Thomas B; Thursz, Mark R; Marchesi, Julian R.
Affiliation
  • Mullish BH; Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
  • McDonald JAK; Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
  • Pechlivanis A; Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
  • Allegretti JR; Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Kao D; Harvard Medical School, Harvard University, Boston, Massachusetts, USA.
  • Barker GF; Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
  • Kapila D; Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
  • Petrof EO; Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
  • Joyce SA; Division of Infectious Diseases/ GI Diseases Research Unit Wing, Department of Medicine, Kingston General Hospital, Queen's University, Kingston, Ontario, Canada.
  • Gahan CGM; APC Microbiome Institute, University College Cork, Cork, Ireland.
  • Glegola-Madejska I; School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
  • Williams HRT; APC Microbiome Institute, University College Cork, Cork, Ireland.
  • Holmes E; School of Pharmacy, University College Cork, Cork, Ireland.
  • Clarke TB; MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, UK.
  • Thursz MR; Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
  • Marchesi JR; Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
Gut ; 68(10): 1791-1800, 2019 10.
Article in En | MEDLINE | ID: mdl-30816855

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Bacterial / Clostridioides difficile / Clostridium Infections / Fecal Microbiota Transplantation / Gastrointestinal Microbiome / Amidohydrolases Limits: Animals / Female / Humans Language: En Journal: Gut Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Bacterial / Clostridioides difficile / Clostridium Infections / Fecal Microbiota Transplantation / Gastrointestinal Microbiome / Amidohydrolases Limits: Animals / Female / Humans Language: En Journal: Gut Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom