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Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care.
Chung, Ha Uk; Kim, Bong Hoon; Lee, Jong Yoon; Lee, Jungyup; Xie, Zhaoqian; Ibler, Erin M; Lee, KunHyuck; Banks, Anthony; Jeong, Ji Yoon; Kim, Jongwon; Ogle, Christopher; Grande, Dominic; Yu, Yongjoon; Jang, Hokyung; Assem, Pourya; Ryu, Dennis; Kwak, Jean Won; Namkoong, Myeong; Park, Jun Bin; Lee, Yechan; Kim, Do Hoon; Ryu, Arin; Jeong, Jaeseok; You, Kevin; Ji, Bowen; Liu, Zhuangjian; Huo, Qingze; Feng, Xue; Deng, Yujun; Xu, Yeshou; Jang, Kyung-In; Kim, Jeonghyun; Zhang, Yihui; Ghaffari, Roozbeh; Rand, Casey M; Schau, Molly; Hamvas, Aaron; Weese-Mayer, Debra E; Huang, Yonggang; Lee, Seung Min; Lee, Chi Hwan; Shanbhag, Naresh R; Paller, Amy S; Xu, Shuai; Rogers, John A.
Affiliation
  • Chung HU; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Kim BH; Department of Electrical Engineering and Computer Science, Northwestern University, Evanston, IL 60208, USA.
  • Lee JY; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Lee J; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Xie Z; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Ibler EM; Center for Bio-integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
  • Lee K; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Banks A; Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Jeong JY; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Kim J; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Ogle C; Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Grande D; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Yu Y; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Jang H; Center for Autonomic Medicine, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
  • Assem P; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Ryu D; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Kwak JW; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Namkoong M; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Park JB; Center for Bio-integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
  • Lee Y; Loomis Laboratory of Physics, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Kim DH; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Ryu A; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Jeong J; Department of Mechanical Engineering, Kyung Hee University, Yongin 17104, Republic of Korea.
  • You K; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Ji B; Center for Bio-integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
  • Liu Z; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Huo Q; Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Feng X; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Deng Y; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Xu Y; Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Jang KI; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Kim J; Center for Bio-integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
  • Zhang Y; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Ghaffari R; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Rand CM; Simpson Querrey Institute, Northwestern University, Chicago, IL 60611, USA.
  • Schau M; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Hamvas A; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Weese-Mayer DE; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Huang Y; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Lee SM; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Lee CH; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Shanbhag NR; Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Paller AS; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Xu S; Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA.
  • Rogers JA; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
Science ; 363(6430)2019 Mar 01.
Article in En | MEDLINE | ID: mdl-30819934
ABSTRACT
Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intensive Care, Neonatal / Electronics / Wireless Technology / Monitoring, Physiologic Type of study: Diagnostic_studies / Observational_studies Limits: Humans / Newborn Language: En Journal: Science Year: 2019 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Intensive Care, Neonatal / Electronics / Wireless Technology / Monitoring, Physiologic Type of study: Diagnostic_studies / Observational_studies Limits: Humans / Newborn Language: En Journal: Science Year: 2019 Document type: Article Affiliation country: United States