Transcriptome patterns in hidradenitis suppurativa: support for the role of antimicrobial peptides and interferon pathways in disease pathogenesis.

Shanmugam, V K; Jones, D; McNish, S; Bendall, M L; Crandall, K A

Shanmugam, V K; Jones, D; McNish, S; Bendall, M L; Crandall, K A.

Affiliation

Shanmugam VK; Division of Rheumatology, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
Jones D; Division of Rheumatology, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
McNish S; Division of Rheumatology, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.
Bendall ML; Computational Biology Institute, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Crandall KA; Department of Microbiology, Immunology and Tropical Medicine, School of Medicine and Health Sciences, George Washington University, Washington, DC, USA.

Clin Exp Dermatol ; 44(8): 882-892, 2019 Dec.

Article in En | MEDLINE | ID: mdl-30828847

Subject(s)

Hidradenitis Suppurativa/metabolism; Interferons/metabolism; Interleukin-1/metabolism; Peptides/metabolism; RNA, Messenger/metabolism; Transcriptome; Adult; Case-Control Studies; Female; Hidradenitis Suppurativa/genetics; Humans; Leukocytes/metabolism; Linear Models; Male; Metabolic Networks and Pathways; Oligonucleotide Array Sequence Analysis; Reference Values; Signal Transduction; Skin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / RNA, Messenger / Interferons / Interleukin-1 / Hidradenitis Suppurativa / Transcriptome Type of study: Etiology_studies / Observational_studies / Prognostic_studies Limits: Adult / Female / Humans / Male Language: En Journal: Clin Exp Dermatol Year: 2019 Document type: Article Affiliation country: United States Country of publication: United kingdom

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