Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors.

Chen, Fangjun; Zou, Zhengyun; Du, Juan; Su, Shu; Shao, Jie; Meng, Fanyan; Yang, Ju; Xu, Qiuping; Ding, Naiqing; Yang, Yang; Liu, Qin; Wang, Qin; Sun, Zhichen; Zhou, Shujuan; Du, Shiyao; Wei, Jia; Liu, Baorui

Chen, Fangjun; Zou, Zhengyun; Du, Juan; Su, Shu; Shao, Jie; Meng, Fanyan; Yang, Ju; Xu, Qiuping; Ding, Naiqing; Yang, Yang; Liu, Qin; Wang, Qin; Sun, Zhichen; Zhou, Shujuan; Du, Shiyao; Wei, Jia; Liu, Baorui.

J Clin Invest ; 129(5): 2056-2070, 2019 05 01.

Article in En | MEDLINE | ID: mdl-30835255

Subject(s)

Antigens, Neoplasm/immunology; Immunotherapy/methods; Mutation; Neoplasms/therapy; Adult; Aged; Cancer Vaccines/immunology; Computational Biology; Disease-Free Survival; Epitopes/immunology; Female; Genomics; HLA-A2 Antigen/immunology; Humans; Immune System; Immunologic Factors; Immunophenotyping; Inhibitory Concentration 50; Male; Middle Aged; Neoplasm Metastasis; Neoplasms/immunology; Pancreatic Neoplasms/immunology; Peptides/immunology; Phenotype; Polymerase Chain Reaction; Precision Medicine/methods; T-Lymphocytes/immunology; Thymoma/immunology; Thymoma/metabolism; Translational Research, Biomedical; Young Adult

Key words

Antigen; Cancer immunotherapy; Immunology; Oncology; T cells

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunotherapy / Mutation / Antigens, Neoplasm / Neoplasms Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Clin Invest Year: 2019 Document type: Article Country of publication: United States

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