A case series of anaphylaxis to chlorhexidine-impregnated central venous catheters in cardiac surgical patients.
Anaesth Intensive Care
; 47(1): 85-89, 2019 Jan.
Article
in En
| MEDLINE
| ID: mdl-30864478
ABSTRACT
We report a case series of anaphylaxis to chlorhexidine-coated central venous catheters (CVCs) when used in cardiac surgical patients in our institution. Our experience, together with increasing reports of anaphylaxis to chlorhexidine-coated CVCs from other sources indicates that chlorhexidine-coated CVCs are not without additional risk. Attempts to lower rates of catheter-related bloodstream infection has led to the widespread adoption of chlorhexidine-coated CVCs in the perioperative and critical care setting, including for routine cardiac surgery. However, closer scrutiny indicates that there is lack of strong evidence demonstrating a meaningful reduction in rates of sepsis or serious morbidity, especially with CVC dwell times of less than seven days. Given the lack of clear benefit, we recommend non-coated CVCs for routine cardiac surgery, with even consideration for chlorhexidine-coated CVCs when specifically indicated for patients at high risk of CVC infection.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chlorhexidine
/
Central Venous Catheters
/
Cardiac Surgical Procedures
/
Anaphylaxis
Limits:
Humans
Language:
En
Journal:
Anaesth Intensive Care
Year:
2019
Document type:
Article
Affiliation country:
Australia