Critical role of the finger loop in arrestin binding to the receptors.

Zheng, Chen; Tholen, Jonas; Gurevich, Vsevolod V

Zheng, Chen; Tholen, Jonas; Gurevich, Vsevolod V.

Affiliation

Zheng C; Department of Pharmacology, Vanderbilt University, Nashville, United States of America.
Tholen J; University of Applied Sciences Emden/Leer, Emden, Germany.
Gurevich VV; Department of Pharmacology, Vanderbilt University, Nashville, United States of America.

PLoS One ; 14(3): e0213792, 2019.

Article in En | MEDLINE | ID: mdl-30875392

Subject(s)

Arrestins/metabolism; Point Mutation; Receptor, Muscarinic M2/metabolism; Receptors, Adrenergic, beta-2/metabolism; Receptors, Dopamine D1/metabolism; Receptors, Dopamine D2/metabolism; Amino Acid Sequence; Arrestins/chemistry; Arrestins/genetics; HEK293 Cells; Humans; Protein Conformation; Receptor, Muscarinic M2/chemistry; Receptor, Muscarinic M2/genetics; Receptors, Adrenergic, beta-2/chemistry; Receptors, Adrenergic, beta-2/genetics; Receptors, Dopamine D1/chemistry; Receptors, Dopamine D1/genetics; Receptors, Dopamine D2/chemistry; Receptors, Dopamine D2/genetics; Sequence Homology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Dopamine D2 / Receptors, Dopamine D1 / Point Mutation / Receptors, Adrenergic, beta-2 / Arrestins / Receptor, Muscarinic M2 Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States

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