Visualizing the down-regulation of hTERT mRNA expression using gold-nanoflare probes and verifying the correlation with cancer cell apoptosis.

Sun, Hongxiao; Hong, Min; Yang, Qiangqiang; Li, Chuan; Zhang, Guangzhi; Yue, Qiaoli; Ma, Yanhua; Li, Xia; Li, Chen-Zhong

Sun, Hongxiao; Hong, Min; Yang, Qiangqiang; Li, Chuan; Zhang, Guangzhi; Yue, Qiaoli; Ma, Yanhua; Li, Xia; Li, Chen-Zhong.

Affiliation

Sun H; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Hong M; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Yang Q; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Li C; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Zhang G; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Yue Q; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Ma Y; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Li X; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com.
Li CZ; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, P. R. China. hongminlcu@163.com and Nanobioengineering/Bioelectronics Laboratory, Department of Biomedical Engineering, Florida International University, Miami, 33174, USA. licz@fiu.edu.

Analyst ; 144(9): 2994-3004, 2019 May 07.

Article in En | MEDLINE | ID: mdl-30892312

Subject(s)

DNA/chemistry; Fluorescent Dyes/chemistry; Gold/chemistry; Metal Nanoparticles/chemistry; RNA, Messenger/metabolism; Telomerase/metabolism; Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacology; Antineoplastic Agents/toxicity; Apoptosis/drug effects; Carbocyanines/chemistry; Catechin/analogs & derivatives; Catechin/pharmacology; Cell Line, Tumor; Cell Survival/drug effects; DNA/toxicity; Down-Regulation; Enzyme Inhibitors/pharmacology; Fluorescence; G1 Phase Cell Cycle Checkpoints/drug effects; Gene Expression Regulation, Neoplastic/drug effects; Humans; Metal Nanoparticles/toxicity; Microscopy, Confocal/methods; Microscopy, Fluorescence/methods; Nucleic Acid Hybridization; Oligonucleotides/chemistry; Oligonucleotides/genetics; Oligonucleotides/toxicity; Oligonucleotides, Antisense/chemistry; Oligonucleotides, Antisense/genetics; Oligonucleotides, Antisense/toxicity; RNA, Messenger/genetics; Telomerase/antagonists & inhibitors; Telomerase/genetics; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / RNA, Messenger / Telomerase / Metal Nanoparticles / Fluorescent Dyes / Gold Limits: Humans Language: En Journal: Analyst Year: 2019 Document type: Article

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