Preservation of fertility in patients with cancer (Review).
Oncol Rep
; 41(5): 2607-2614, 2019 May.
Article
in En
| MEDLINE
| ID: mdl-30896846
ABSTRACT
Survival rates in oncological patients have been steadily increasing in recent years due to the greater effectiveness of novel oncological treatments, such as radio and chemotherapy. However, these treatments impair the reproductive ability of patients, and may cause premature ovarian failure in females and azoospermia in males. Fertility preservation in both female and male oncological patients is nowadays possible and should be integrated as part of the oncological healthcare. The main objective of this review was to describe the different existing options of fertility preservation in patients undergoing gonadotoxic cancer treatments, as well as the differences in success rates that may appear in the different techniques evaluated. Emerging techniques are promising, such as the cryopreservation in orthotopic models of ovarian or testicle tissues, artificial ovaries, or in vitro culture prior to the autotransplantation of cryopreserved tissues. However, oocyte vitrification for female patients and sperm banking for male patients are considered the first line fertility preservation option at the present time for cancer patients undergoing treatment. Certainly, new fertility preservation techniques will continue to develop in the following years. However, despite the growing advances in the subject, optimal counselling from healthcare professionals should always be present.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Fertility Preservation
/
Cancer Survivors
/
Neoplasms
/
Antineoplastic Agents
Limits:
Female
/
Humans
/
Male
Language:
En
Journal:
Oncol Rep
Journal subject:
NEOPLASIAS
Year:
2019
Document type:
Article
Affiliation country:
Spain