Mitochondrial origins of fractional control in regulated cell death.

Santos, Luís C; Vogel, Robert; Chipuk, Jerry E; Birtwistle, Marc R; Stolovitzky, Gustavo; Meyer, Pablo

Santos, Luís C; Vogel, Robert; Chipuk, Jerry E; Birtwistle, Marc R; Stolovitzky, Gustavo; Meyer, Pablo.

Affiliation

Santos LC; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Vogel R; IBM T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY, 10598, USA.
Chipuk JE; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Birtwistle MR; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Stolovitzky G; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY, 10029, USA.
Meyer P; Systems Biology Center New York, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. mbirtwi@clemson.edu.

Nat Commun ; 10(1): 1313, 2019 03 21.

Article in En | MEDLINE | ID: mdl-30899020

Subject(s)

Apoptosis/drug effects; Gene Expression Regulation, Neoplastic; Mitochondria/drug effects; TNF-Related Apoptosis-Inducing Ligand/pharmacology; bcl-2 Homologous Antagonist-Killer Protein/genetics; bcl-2-Associated X Protein/genetics; Annexin A5/chemistry; Biomarkers/metabolism; Cell Line, Tumor; Cell Survival/drug effects; Epithelial Cells/drug effects; Epithelial Cells/metabolism; Epithelial Cells/pathology; Fluorescent Dyes/chemistry; Genetic Variation; HeLa Cells; Humans; Jurkat Cells; Mitochondria/genetics; Mitochondria/metabolism; Mitochondria/pathology; Models, Genetic; Organic Chemicals/chemistry; bcl-2 Homologous Antagonist-Killer Protein/metabolism; bcl-2-Associated X Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Apoptosis / Bcl-2-Associated X Protein / Bcl-2 Homologous Antagonist-Killer Protein / TNF-Related Apoptosis-Inducing Ligand / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Document type: Article Affiliation country: United States Country of publication: United kingdom

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