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Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation.
Catanese, Alberto; Olde Heuvel, Florian; Mulaw, Medhanie; Demestre, Maria; Higelin, Julia; Barbi, Gotthold; Freischmidt, Axel; Weishaupt, Jochen H; Ludolph, Albert C; Roselli, Francesco; Boeckers, Tobias M.
Affiliation
  • Catanese A; Institute of Anatomy and Cell Biology, Ulm University , Ulm , DE , Germany.
  • Olde Heuvel F; International Graduate School, Ulm University , Ulm , DE , Germany.
  • Mulaw M; Deptartment of Neurology, Ulm University , Ulm , DE , Germany.
  • Demestre M; Institute of Experimental Tumor Research, Ulm University , Ulm , DE , Germany.
  • Higelin J; Institute of Anatomy and Cell Biology, Ulm University , Ulm , DE , Germany.
  • Barbi G; Institute of Anatomy and Cell Biology, Ulm University , Ulm , DE , Germany.
  • Freischmidt A; International Graduate School, Ulm University , Ulm , DE , Germany.
  • Weishaupt JH; Institute for Human Genetics, Ulm University , Ulm , DE , Germany.
  • Ludolph AC; Deptartment of Neurology, Ulm University , Ulm , DE , Germany.
  • Roselli F; Deptartment of Neurology, Ulm University , Ulm , DE , Germany.
  • Boeckers TM; Deptartment of Neurology, Ulm University , Ulm , DE , Germany.
Autophagy ; 15(10): 1719-1737, 2019 10.
Article in En | MEDLINE | ID: mdl-30939964
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Tretinoin / Protein Serine-Threonine Kinases / Vesicular Transport Proteins / Induced Pluripotent Stem Cells / Sequestosome-1 Protein / Autophagy-Related Proteins / Motor Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Autophagy Year: 2019 Document type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Tretinoin / Protein Serine-Threonine Kinases / Vesicular Transport Proteins / Induced Pluripotent Stem Cells / Sequestosome-1 Protein / Autophagy-Related Proteins / Motor Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Autophagy Year: 2019 Document type: Article Affiliation country: Germany