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Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis.
Esther, Charles R; Muhlebach, Marianne S; Ehre, Camille; Hill, David B; Wolfgang, Matthew C; Kesimer, Mehmet; Ramsey, Kathryn A; Markovetz, Matthew R; Garbarine, Ian C; Forest, M Gregory; Seim, Ian; Zorn, Bryan; Morrison, Cameron B; Delion, Martial F; Thelin, William R; Villalon, Diane; Sabater, Juan R; Turkovic, Lidija; Ranganathan, Sarath; Stick, Stephen M; Boucher, Richard C.
Affiliation
  • Esther CR; Division of Pediatric Pulmonology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. charles_esther@med.unc.edu.
  • Muhlebach MS; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Ehre C; Division of Pediatric Pulmonology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Hill DB; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Wolfgang MC; Division of Pediatric Pulmonology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Kesimer M; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Ramsey KA; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Markovetz MR; Department of Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Garbarine IC; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Forest MG; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Seim I; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Zorn B; Telethon Kids Institute, University of Western Australia, Perth 6009, Australia.
  • Morrison CB; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Delion MF; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Thelin WR; Departments of Mathematics, Biomedical Engineering, and Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Villalon D; Departments of Mathematics, Biomedical Engineering, and Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Sabater JR; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Turkovic L; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Ranganathan S; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Stick SM; Parion Sciences, Durham, NC 27713, USA.
  • Boucher RC; Parion Sciences, Durham, NC 27713, USA.
Sci Transl Med ; 11(486)2019 04 03.
Article in En | MEDLINE | ID: mdl-30944166
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cystic Fibrosis / Lung / Mucus Type of study: Observational_studies / Risk_factors_studies Limits: Animals / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cystic Fibrosis / Lung / Mucus Type of study: Observational_studies / Risk_factors_studies Limits: Animals / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article Affiliation country: United States