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Successful clozapine rechallenge in a patient with suspected drug induced lupus.
Pathak, Suraj; Cherry, Scott; Samad, Samreen; Aftab, Ambreen.
Affiliation
  • Pathak S; Department of Cardiovascular Sciences and NIHR Leicester Biomedical Research Unit in Cardiovascular Medicine, Glenfield Hospital, Leicester, UK.
  • Cherry S; Department of Psychiatry, St Mary's Hospital, Forest Centre, Northamptonshire, UK.
  • Samad S; Department of Psychiatry, Welland Centre, Northamptonshire, UK.
  • Aftab A; Department of Psychiatry, Welland Centre, Northamptonshire, UK.
BMJ Case Rep ; 12(4)2019 Apr 03.
Article in En | MEDLINE | ID: mdl-30948402
Clozapine is the most effective treatment for patients with refractory schizophrenia. Clozapine is also associated with serious and potentially lethal side effects including drug induced lupus (DIL). There have been four previous published case reports describing clozapine inducing a lupus-like syndrome including one previous case where a clozapine rechallenge was attempted without success. This case report describes a successful clozapine rechallenge in a patient with suspected DIL.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents / Clozapine / Lupus Erythematosus, Systemic Limits: Humans Language: En Journal: BMJ Case Rep Year: 2019 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents / Clozapine / Lupus Erythematosus, Systemic Limits: Humans Language: En Journal: BMJ Case Rep Year: 2019 Document type: Article Country of publication: United kingdom