Cyclodextrin-Polypyrrole Coatings of Scaffolds for Tissue Engineering.
Polymers (Basel)
; 11(3)2019 Mar 11.
Article
in En
| MEDLINE
| ID: mdl-30960443
ABSTRACT
Polypyrrole is one of the most investigated conductive polymers used for tissue engineering applications because of its advantageous properties and the ability to promote different cell types' adhesion and proliferation. Together with ß-cyclodextrin, which is capable of accommodating helpful biomolecules in its cavity, it would make a perfect couple for use as a scaffold for tissue engineering. Such scaffolds were prepared by the polymerisation of 6-(pyrrol-3-yl)hexanoic acid on polycaprolactone microfibres with subsequent attachment of ß-cyclodextrin on the polypyrrole layer. The materials were deeply characterised by several physical and spectroscopic techniques. Testing of the cyclodextrin enriched composite scaffold revealed its better performance in in vitro experiments compared with pristine polycaprolactone or polypyrrole covered polycaprolactone scaffolds.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Polymers (Basel)
Year:
2019
Document type:
Article
Affiliation country:
Czech Republic