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C9orf72 Poly(PR) Dipeptide Repeats Disturb Biomolecular Phase Separation and Disrupt Nucleolar Function.
White, Michael R; Mitrea, Diana M; Zhang, Peipei; Stanley, Christopher B; Cassidy, Devon E; Nourse, Amanda; Phillips, Aaron H; Tolbert, Michele; Taylor, J Paul; Kriwacki, Richard W.
Affiliation
  • White MR; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Mitrea DM; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Zhang P; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Stanley CB; Large Scale Structures Group, Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830, USA.
  • Cassidy DE; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Nourse A; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Molecular Interaction Analysis Shared Resource, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Phillips AH; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Tolbert M; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Taylor JP; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
  • Kriwacki RW; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN 38105, USA. Electronic address: richard.kriwacki@stjude.org.
Mol Cell ; 74(4): 713-728.e6, 2019 05 16.
Article in En | MEDLINE | ID: mdl-30981631
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Repetitive Sequences, Amino Acid / C9orf72 Protein / Amyotrophic Lateral Sclerosis Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Repetitive Sequences, Amino Acid / C9orf72 Protein / Amyotrophic Lateral Sclerosis Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States