Transforming Growth Factor Beta-1 in Human Breast Milk and Its Correlation with Infants' Parameters.
Breastfeed Med
; 14(6): 404-407, 2019.
Article
in En
| MEDLINE
| ID: mdl-30990330
ABSTRACT
Background:
Breastfeeding provides optimal nutrition and health protection for the infant; it contains many anti-inflammatory factors, including transforming growth factor beta-1 (TGF-ß1). Our study aimed to measure the level of TGF-ß1 in human milk and to find its correlation with some infant anthropometric characteristics. Subjects andMethods:
A milk sample was collected from 84 mothers and the level of TGF-ß1 was measured using enzyme-linked immunosorbent assay.Results:
TGF-ß1 was significantly higher in vegetarian mothers compared with nonvegetarian mothers (p = 0.044). Additionally, the mean value of breast milk TGF-ß1 was significantly higher in mothers using contraceptive pills compared with those who do not (p = 0.021). Also, the mean value of TGF-ß1 was significantly higher in infants 3-6 months than those <3 months (p = 0.010); also there was a significant difference regarding infants' weight and length with average weight and length (p = 0.042) and (p = 0.009), respectively.Conclusions:
TGF-ß1 in human milk may play a role in infants' growth and development; mothers' diet is known to influence TGF-ß1 level and its relation to infants' age and weight. Contraceptive method could have an influence on TGF-ß1 levels during breastfeeding.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Breast Feeding
/
Child Development
/
Transforming Growth Factor beta1
/
Milk, Human
Type of study:
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Language:
En
Journal:
Breastfeed Med
Journal subject:
CIENCIAS DA NUTRICAO
Year:
2019
Document type:
Article
Affiliation country:
Egypt