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Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment.
Wu, Adela; Maxwell, Russell; Xia, Yuanxuan; Cardarelli, Pina; Oyasu, Miho; Belcaid, Zineb; Kim, Eileen; Hung, Alice; Luksik, Andrew S; Garzon-Muvdi, Tomas; Jackson, Christopher M; Mathios, Dimitrios; Theodros, Debebe; Cogswell, John; Brem, Henry; Pardoll, Drew M; Lim, Michael.
Affiliation
  • Wu A; Department of Neurosurgery, Stanford Health Care, Stanford, CA, 94304, USA.
  • Maxwell R; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Xia Y; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Cardarelli P; Bristol-Myers Squibb, New York, NY, USA.
  • Oyasu M; Bristol-Myers Squibb, New York, NY, USA.
  • Belcaid Z; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Kim E; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Hung A; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Luksik AS; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Garzon-Muvdi T; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Jackson CM; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Mathios D; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Theodros D; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Cogswell J; Bristol-Myers Squibb, New York, NY, USA.
  • Brem H; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA.
  • Pardoll DM; Department of Oncology, Johns Hopkins Hospital, Baltimore, MD, USA.
  • Lim M; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, 21205, USA. mlim3@jhmi.edu.
J Neurooncol ; 143(2): 241-249, 2019 Jun.
Article in En | MEDLINE | ID: mdl-31025274
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Receptors, CXCR4 / Myeloid Cells / Programmed Cell Death 1 Receptor / Antineoplastic Agents, Immunological / Immunotherapy Type of study: Clinical_trials Limits: Animals / Female / Humans Language: En Journal: J Neurooncol Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Receptors, CXCR4 / Myeloid Cells / Programmed Cell Death 1 Receptor / Antineoplastic Agents, Immunological / Immunotherapy Type of study: Clinical_trials Limits: Animals / Female / Humans Language: En Journal: J Neurooncol Year: 2019 Document type: Article Affiliation country: United States Country of publication: United States