Suppression of autophagy enhances preferential toxicity of epothilone A and epothilone B in ovarian cancer cells.

Rogalska, Aneta; Gajek, Arkadiusz; Marczak, Agnieszka

Rogalska, Aneta; Gajek, Arkadiusz; Marczak, Agnieszka.

Affiliation

Rogalska A; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland. Electronic address: aneta.rogalska@biol.uni.lodz.pl.
Gajek A; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.
Marczak A; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.

Phytomedicine ; 61: 152847, 2019 Aug.

Article in En | MEDLINE | ID: mdl-31029905

Subject(s)

Antineoplastic Agents/pharmacology; Autophagy/drug effects; Epothilones/pharmacology; Ovarian Neoplasms/drug therapy; Apoptosis/drug effects; Caspase 3/metabolism; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Macrolides/pharmacology; Microtubules/drug effects; Ovarian Neoplasms/pathology; Paclitaxel/pharmacology

Key words

Apoptosis; Autophagy; Cell death; Epothilones; Ovarian cancer; Paclitaxel

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Autophagy / Epothilones / Antineoplastic Agents Limits: Female / Humans Language: En Journal: Phytomedicine Journal subject: TERAPIAS COMPLEMENTARES Year: 2019 Document type: Article Country of publication: Germany

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