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Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Cao, Lei; Liu, Pi; Yang, Pan; Gao, Qiang; Li, Hong; Sun, Yao; Zhu, Ling; Lin, Jianping; Su, Dan; Rao, Zihe; Wang, Xiangxi.
Affiliation
  • Cao L; CAS Key Laboratory of Infection and Immunity, CAS Centre for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Liu P; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu, China.
  • Yang P; National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Gao Q; Biodesign Center, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
  • Li H; CAS Key Laboratory of Infection and Immunity, CAS Centre for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Sun Y; National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Zhu L; Sinovac Biotech Co., Ltd., Beijing, China.
  • Lin J; Tianjin International Biomedical Joint Research Institute, Tianjin, China.
  • Su D; CAS Key Laboratory of Infection and Immunity, CAS Centre for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Rao Z; National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Wang X; CAS Key Laboratory of Infection and Immunity, CAS Centre for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
PLoS Biol ; 17(4): e3000229, 2019 04.
Article in En | MEDLINE | ID: mdl-31039149
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Hepatitis A virus / Antibodies, Neutralizing Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: China Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Hepatitis A virus / Antibodies, Neutralizing Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2019 Document type: Article Affiliation country: China Country of publication: United States