Downregulation of microRNA-205 inhibits cell invasion and angiogenesis of cervical cancer through TSLC1-mediated Akt signaling pathway.

Zhang, Fang; Liu, Jian; Xie, Bei-Bei

Zhang, Fang; Liu, Jian; Xie, Bei-Bei.

Affiliation

Zhang F; Gynecology Ward-1, Linyi People's Hospital, Linyi, P. R. China.
Liu J; Department of Gynaecology, Yuebei People's Hospital, Shaoguan, P. R. China.
Xie BB; Gynecology Ward-1, Linyi People's Hospital, Linyi, P. R. China.

J Cell Physiol ; 234(10): 18626-18638, 2019 08.

Article in En | MEDLINE | ID: mdl-31049956

Subject(s)

Cell Adhesion Molecule-1/metabolism; Down-Regulation/genetics; MicroRNAs/genetics; Neovascularization, Pathologic/genetics; Proto-Oncogene Proteins c-akt/metabolism; Signal Transduction; Uterine Cervical Neoplasms/blood supply; Uterine Cervical Neoplasms/genetics; Animals; Base Sequence; Carcinogenesis/genetics; Carcinogenesis/pathology; Cell Adhesion Molecule-1/genetics; Cell Line, Tumor; Cell Movement/genetics; Female; Gene Expression Regulation, Neoplastic; Humans; Mice, Inbred BALB C; Mice, Nude; MicroRNAs/metabolism; Microvessels/pathology; Models, Biological; Neoplasm Invasiveness; Protein Binding; Up-Regulation/genetics; Uterine Cervical Neoplasms/pathology

Key words

angiogenesis; cervical cancer (CC); invasion; microRNA-205 (miR-205); migration; tumor suppressor lung cancer 1 (TSLC1)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Down-Regulation / Uterine Cervical Neoplasms / MicroRNAs / Proto-Oncogene Proteins c-akt / Cell Adhesion Molecule-1 / Neovascularization, Pathologic Limits: Animals / Female / Humans Language: En Journal: J Cell Physiol Year: 2019 Document type: Article Country of publication: United States

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