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Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes.
Kallen, Joerg; Izaac, Aude; Chau, Suzanne; Wirth, Emmanuelle; Schoepfer, Joseph; Mah, Robert; Schlapbach, Achim; Stutz, Stefan; Vaupel, Andrea; Guagnano, Vito; Masuya, Keiichi; Stachyra, Therese-Marie; Salem, Bahaa; Chene, Patrick; Gessier, Francois; Holzer, Philipp; Furet, Pascal.
Affiliation
  • Kallen J; Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Izaac A; Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Chau S; Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Wirth E; Chemical Biology & Therapeutics, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Schoepfer J; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Mah R; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Schlapbach A; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Stutz S; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Vaupel A; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Guagnano V; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Masuya K; Present address: Peptidream Inc., Menguro, Tokyo, Japan.
  • Stachyra TM; Disease Area Oncology, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Salem B; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Chene P; Disease Area Oncology, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Gessier F; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Holzer P; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
  • Furet P; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Novartis Campus, 4002, Basel, Switzerland.
ChemMedChem ; 14(14): 1305-1314, 2019 07 17.
Article in En | MEDLINE | ID: mdl-31066983
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Cell Cycle Proteins / Proto-Oncogene Proteins c-mdm2 / Heterocyclic Compounds Limits: Humans Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2019 Document type: Article Affiliation country: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Cell Cycle Proteins / Proto-Oncogene Proteins c-mdm2 / Heterocyclic Compounds Limits: Humans Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2019 Document type: Article Affiliation country: Switzerland