Closed-Loop Systems and In Vitro Neuronal Cultures: Overview and Applications.
Adv Neurobiol
; 22: 351-387, 2019.
Article
in En
| MEDLINE
| ID: mdl-31073944
ABSTRACT
One of the main limitations preventing the realization of a successful dialogue between the brain and a putative enabling device is the intricacy of brain signals. In this perspective, closed-loop in vitro systems can be used to investigate the interactions between a network of neurons and an external system, such as an interacting environment or an artificial device. In this chapter, we provide an overview of closed-loop in vitro systems, which have been developed for investigating potential neuroprosthetic applications. In particular, we first explore how to modify or set a target dynamical behavior in a network of neurons. We then analyze the behavior of in vitro systems connected to artificial devices, such as robots. Finally, we provide an overview of biological neuronal networks interacting with artificial neuronal networks, a configuration currently offering a promising solution for clinical applications.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
In Vitro Techniques
/
Robotics
/
Neural Networks, Computer
/
Cell Culture Techniques
/
Nerve Net
/
Neurons
Limits:
Humans
Language:
En
Journal:
Adv Neurobiol
Year:
2019
Document type:
Article
Affiliation country:
Italy