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The Notch signaling pathway inhibitor Dapt alleviates autism-like behavior, autophagy and dendritic spine density abnormalities in a valproic acid-induced animal model of autism.
Zhang, Yinghua; Xiang, Zhe; Jia, Yunjie; He, Xueling; Wang, Lijun; Cui, Weigang.
Affiliation
  • Zhang Y; Department of Human Anatomy, Xinxiang Medical University, Xinxiang, Henan 453003, PR China; Key Laboratory for Molecular Neurology of Xinxiang, Xinxiang, Henan 453003, PR China. Electronic address: zyhflo2013@163.com.
  • Xiang Z; Department of Human Anatomy, Xinxiang Medical University, Xinxiang, Henan 453003, PR China; Key Laboratory for Molecular Neurology of Xinxiang, Xinxiang, Henan 453003, PR China.
  • Jia Y; Department of Human Anatomy, Xinxiang Medical University, Xinxiang, Henan 453003, PR China; Key Laboratory for Molecular Neurology of Xinxiang, Xinxiang, Henan 453003, PR China.
  • He X; Department of Human Anatomy, Xinxiang Medical University, Xinxiang, Henan 453003, PR China; Key Laboratory for Molecular Neurology of Xinxiang, Xinxiang, Henan 453003, PR China.
  • Wang L; Department of Human Anatomy, Xinxiang Medical University, Xinxiang, Henan 453003, PR China; Key Laboratory for Molecular Neurology of Xinxiang, Xinxiang, Henan 453003, PR China.
  • Cui W; Department of Human Anatomy, Xinxiang Medical University, Xinxiang, Henan 453003, PR China; Key Laboratory for Molecular Neurology of Xinxiang, Xinxiang, Henan 453003, PR China.
Prog Neuropsychopharmacol Biol Psychiatry ; 94: 109644, 2019 08 30.
Article in En | MEDLINE | ID: mdl-31075347
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autophagy / Dendritic Spines / Dipeptides / Receptor, Notch1 Limits: Animals / Pregnancy Language: En Journal: Prog Neuropsychopharmacol Biol Psychiatry Year: 2019 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Autophagy / Dendritic Spines / Dipeptides / Receptor, Notch1 Limits: Animals / Pregnancy Language: En Journal: Prog Neuropsychopharmacol Biol Psychiatry Year: 2019 Document type: Article Country of publication: United kingdom