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Novel triazine-based pyrimidines suppress glomerular mesangial cells proliferation and matrix protein accumulation through a ROS-dependent mechanism in the diabetic milieu.
Diab El-Harakeh, Mira; Njeim, Rachel; Youssef, Ali; Youssef, Natalie; Eid, Assaad A; Bouhadir, Kamal H.
Affiliation
  • Diab El-Harakeh M; Department of Chemistry, Faculty of Arts and Sciences, American University of Beirut, Beirut, Lebanon.
  • Njeim R; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
  • Youssef A; Department of Chemistry, Faculty of Arts and Sciences, American University of Beirut, Beirut, Lebanon.
  • Youssef N; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
  • Eid AA; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon. Electronic address: ae49@aub.edu.lb.
  • Bouhadir KH; Department of Chemistry, Faculty of Arts and Sciences, American University of Beirut, Beirut, Lebanon. Electronic address: kb05@aub.edu.lb.
Bioorg Med Chem Lett ; 29(13): 1580-1585, 2019 07 01.
Article in En | MEDLINE | ID: mdl-31078409
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Diabetic Nephropathies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Document type: Article Affiliation country: Lebanon Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Diabetic Nephropathies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Document type: Article Affiliation country: Lebanon Country of publication: United kingdom