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CF2H, a Functional Group-Dependent Hydrogen-Bond Donor: Is It a More or Less Lipophilic Bioisostere of OH, SH, and CH3?
Zafrani, Yossi; Sod-Moriah, Gali; Yeffet, Dina; Berliner, Anat; Amir, Dafna; Marciano, Daniele; Elias, Shlomi; Katalan, Shahaf; Ashkenazi, Nissan; Madmon, Moran; Gershonov, Eytan; Saphier, Sigal.
Affiliation
  • Zafrani Y; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Sod-Moriah G; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Yeffet D; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Berliner A; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Amir D; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Marciano D; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Elias S; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Katalan S; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Ashkenazi N; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Madmon M; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Gershonov E; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
  • Saphier S; The Department of Organic Chemistry , Israel Institute for Biological Research , Ness-Ziona 74100 , Israel.
J Med Chem ; 62(11): 5628-5637, 2019 06 13.
Article in En | MEDLINE | ID: mdl-31091098
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hydrophobic and Hydrophilic Interactions / Fluorocarbons Type of study: Prognostic_studies Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Document type: Article Affiliation country: Israel Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hydrophobic and Hydrophilic Interactions / Fluorocarbons Type of study: Prognostic_studies Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2019 Document type: Article Affiliation country: Israel Country of publication: United States