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IL233, an IL-2-IL-33 hybrid cytokine induces prolonged remission of mouse lupus nephritis by targeting Treg cells as a single therapeutic agent.
Stremska, Marta E; Dai, Chao; Venkatadri, Rajkumar; Wang, Hongyang; Sabapathy, Vikram; Kumar, Gaurav; Jose, Sheethal; Mohammad, Saleh; Sung, Sun-Sang J; Fu, Shu Man; Sharma, Rahul.
Affiliation
  • Stremska ME; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Dai C; Center for Immunity, Inflammation and Regenerative Medicine, Division of Rheumatology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Venkatadri R; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Wang H; Center for Immunity, Inflammation and Regenerative Medicine, Division of Rheumatology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Sabapathy V; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Kumar G; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Jose S; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Mohammad S; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA.
  • Sung SJ; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA; Center for Immunity, Inflammation and Regenerative Medicine, Division of Rheumatology, Department of Medicine, University of Virginia, Charlo
  • Fu SM; Center for Immunity, Inflammation and Regenerative Medicine, Division of Rheumatology, Department of Medicine, University of Virginia, Charlottesville, VA, USA; Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA, USA. Electronic address: sf2e@virgi
  • Sharma R; Center for Immunity, Inflammation and Regenerative Medicine, Division of Nephrology, Department of Medicine, University of Virginia, Charlottesville, VA, USA. Electronic address: rs3wn@virginia.edu.
J Autoimmun ; 102: 133-141, 2019 08.
Article in En | MEDLINE | ID: mdl-31103267
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lupus Nephritis / Recombinant Fusion Proteins / Interleukin-2 / T-Lymphocytes, Regulatory / Interleukin-33 Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lupus Nephritis / Recombinant Fusion Proteins / Interleukin-2 / T-Lymphocytes, Regulatory / Interleukin-33 Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Document type: Article Affiliation country: United States Country of publication: United kingdom