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A feedforward relationship between active Rac1 and phosphorylated Bcl-2 is critical for sustaining Bcl-2 phosphorylation and promoting cancer progression.
Chong, Stephen Jun Fei; Lai, Jolin Xiao Hui; Qu, Jianhua; Hirpara, Jayshree; Kang, Jia; Swaminathan, Kunchithapadam; Loh, Thomas; Kumar, Ansu; Vali, Shireen; Abbasi, Taher; Pervaiz, Shazib.
Affiliation
  • Chong SJF; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore; Medical Science Cluster Cancer Program, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore.
  • Lai JXH; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore.
  • Qu J; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore; Medical Science Cluster Cancer Program, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore.
  • Hirpara J; Cancer Science Institute, NUS, Singapore.
  • Kang J; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore; NUS Graduate School of Integrative Sciences and Engineering, NUS, Singapore.
  • Swaminathan K; Department of Biological Sciences, National University of Singapore (NUS), Singapore.
  • Loh T; Department of Otolaryngology, National University Healthcare System (NUHS), Singapore.
  • Kumar A; Cellworks Research India Private Limited, Bangalore, India.
  • Vali S; Cellworks Group Inc., San Jose, CA, USA.
  • Abbasi T; Cellworks Group Inc., San Jose, CA, USA.
  • Pervaiz S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore; Medical Science Cluster Cancer Program, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore; NUS Graduate School of Integrative Sciences and Engineering, NUS,
Cancer Lett ; 457: 151-167, 2019 08 10.
Article in En | MEDLINE | ID: mdl-31103719
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Proto-Oncogene Proteins c-bcl-2 / Rac1 GTP-Binding Protein / Lymphoma / Melanoma Limits: Humans Language: En Journal: Cancer Lett Year: 2019 Document type: Article Affiliation country: Singapore Country of publication: Ireland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Proto-Oncogene Proteins c-bcl-2 / Rac1 GTP-Binding Protein / Lymphoma / Melanoma Limits: Humans Language: En Journal: Cancer Lett Year: 2019 Document type: Article Affiliation country: Singapore Country of publication: Ireland