Dosage-related beneficial and deleterious effects of ginsenoside Rb1 on mouse oocyte maturation and fertilization and fetal development.

Huang, Chien-Hsun; Wang, Fu-Ting; Chan, Wen-Hsiung

Huang, Chien-Hsun; Wang, Fu-Ting; Chan, Wen-Hsiung.

Affiliation

Huang CH; Department of Obstetrics and Gynecology, Taoyuan General Hospital, Ministry of Health & Welfare, Taoyuan City, Taiwan.
Wang FT; Rehabilitation and Technical Aid Center, Taipei Veterans General Hospital, Taipei City, Taiwan.
Chan WH; Department of Bioscience Technology and Center for Nanotechnology, Chung Yuan Christian University, Taoyuan City, Taiwan.

Environ Toxicol ; 34(9): 1001-1012, 2019 Sep.

Article in En | MEDLINE | ID: mdl-31112002

Subject(s)

Fetal Development/drug effects; Ginsenosides; Oocytes/drug effects; Oogenesis/drug effects; Animals; Apoptosis/drug effects; Blastocyst/drug effects; Blastocyst/metabolism; Dose-Response Relationship, Drug; Embryonic Development/drug effects; Female; Fertilization in Vitro; Ginsenosides/administration & dosage; Ginsenosides/pharmacology; Ginsenosides/toxicity; In Vitro Techniques; Mice; Mice, Inbred ICR; Oocytes/metabolism; Pregnancy; Reactive Oxygen Species/metabolism; Signal Transduction

Key words

ROS; apoptosis; embryonic development; ginsenoside Rb1; oocyte maturation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oocytes / Oogenesis / Ginsenosides / Fetal Development Type of study: Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Environ Toxicol Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2019 Document type: Article Affiliation country: Taiwan Country of publication: United States

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