Off to a Bad Start: Cancer Initiation by Pluripotency Regulator PRDM14.

Tracey, Lauren J; Justice, Monica J

Tracey, Lauren J; Justice, Monica J.

Affiliation

Tracey LJ; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ONT, M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ONT, M5S 1A8, Canada.
Justice MJ; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ONT, M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ONT, M5S 1A8, Canada. Electronic address: monica.justice@sickkids.ca.

Trends Genet ; 35(7): 489-500, 2019 07.

Article in En | MEDLINE | ID: mdl-31130394

Subject(s)

DNA-Binding Proteins/physiology; Neoplasms/genetics; Pluripotent Stem Cells/pathology; RNA-Binding Proteins/physiology; Transcription Factors/physiology; DNA Damage; Epigenesis, Genetic; Genomic Instability; Humans; Neoplasms/pathology

Key words

DNA damage; ETO/CBFA2; PRDM14; cancer stem cell; epigenetics; pluripotency

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / RNA-Binding Proteins / Pluripotent Stem Cells / DNA-Binding Proteins / Neoplasms Limits: Humans Language: En Journal: Trends Genet Journal subject: GENETICA Year: 2019 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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