Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models.

Naini, Raju; Chikati, Rajasekhar; Vudem, Dashavantha Reddy; Kancha, Rama Krishna

Naini, Raju; Chikati, Rajasekhar; Vudem, Dashavantha Reddy; Kancha, Rama Krishna.

Affiliation

Naini R; a Molecular Medicine and Therapeutics Laboratory , Centre for Plant Molecular Biology (CPMB), Osmania University , Hyderabad , India.
Chikati R; a Molecular Medicine and Therapeutics Laboratory , Centre for Plant Molecular Biology (CPMB), Osmania University , Hyderabad , India.
Vudem DR; a Molecular Medicine and Therapeutics Laboratory , Centre for Plant Molecular Biology (CPMB), Osmania University , Hyderabad , India.
Kancha RK; a Molecular Medicine and Therapeutics Laboratory , Centre for Plant Molecular Biology (CPMB), Osmania University , Hyderabad , India.

J Recept Signal Transduct Res ; 39(1): 55-59, 2019 Feb.

Article in En | MEDLINE | ID: mdl-31132911

Subject(s)

Cellular Senescence/drug effects; Imines/chemistry; Longevity; Resveratrol/pharmacology; Saccharomyces cerevisiae/growth & development; Sirtuin 1/metabolism; Stilbenes/pharmacology; Antioxidants/pharmacology; Gene Expression Regulation/drug effects; Humans; K562 Cells; Molecular Docking Simulation; Saccharomyces cerevisiae/drug effects

Key words

Resveratrol; SIRT1; cellular replicative senescence; chronological life span; imine stilbene analogs; molecular docking

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Saccharomyces cerevisiae / Stilbenes / Cellular Senescence / Sirtuin 1 / Resveratrol / Imines / Longevity Type of study: Evaluation_studies Limits: Humans Language: En Journal: J Recept Signal Transduct Res Journal subject: BIOQUIMICA / FISIOLOGIA Year: 2019 Document type: Article Affiliation country: India

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