Preovulatory injection of estradiol-17 beta: effect on noradrenaline activity in different parts of the rabbit oviduct.
Reprod Nutr Dev (1980)
; 27(4): 791-9, 1987.
Article
in En
| MEDLINE
| ID: mdl-3116622
ABSTRACT
This paper compares noradrenaline content in the different parts of the oviduct in rabbits receiving or not a dose of estradiol-17 beta 24 h before human chorionic gonadotropin (HCG) and killed 60 h post HCG. 3,4-Dihydroxyphenylalanine assays were carried out in the oviduct after aromatic L-amino acid decarboxylase was inhibited by m-hydroxybenzylhydrazine (NSD 1015) in the same experimental conditions. Pauerstein et al. (1974) have shown that an intramuscular injection of 250 micrograms of estradiol-17 beta in rabbits 24 h before intravenous injection of 100 IU of HCG delays ovum transport at the ampullary-isthmic junction. The extent of this noradrenergic innervation suggested that estradiol could act at least partially through the noradrenergic systems. Our results show that estradiol-17 beta increased oviduct weight by water retention without modifying either the tyrosine hydroxylase activity or the noradrenaline content in any part of the oviduct and that, consequently, the estrogen-induced "tube locking" of ova was not mediated through the noradrenergic processes.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Norepinephrine
/
Estradiol
/
Fallopian Tubes
Limits:
Animals
Language:
En
Journal:
Reprod Nutr Dev (1980)
Year:
1987
Document type:
Article
Affiliation country:
France