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Intravenous immunoglobulin and rituximab versus placebo treatment of antibody-associated psychosis: study protocol of a randomised phase IIa double-blinded placebo-controlled trial (SINAPPS2).
Lennox, Belinda; Yeeles, Ksenija; Jones, Peter B; Zandi, Michael; Joyce, Eileen; Yu, Ly-Mee; Tomei, Giuliano; Pollard, Rebecca; Vincent, Sally-Anne; Shimazaki, Mio; Cairns, Iona; Dowling, Francis; Kabir, Thomas; Barnes, Thomas R E; Lingford Hughes, Anne; Hosseini, Akram A; Harrower, Timothy; Buckley, Camilla; Coles, Alasdair.
Affiliation
  • Lennox B; Department of Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, UK.
  • Yeeles K; Department of Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, UK.
  • Jones PB; School of Clinical Medicine and Department of Psychiatry, University of Cambridge, Box 189, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK.
  • Zandi M; Department of Neuromuscular Diseases, University College London Queen Square Institute of Neurology, and National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK.
  • Joyce E; University College London Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Box 19, Queen Square, London, WC1N 3BG, UK.
  • Yu LM; Primary Care Clinical Trials Unit, Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK.
  • Tomei G; Department of Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, UK.
  • Pollard R; Department of Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, UK.
  • Vincent SA; Department of Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, UK.
  • Shimazaki M; Department of Psychiatry, University of Oxford and Oxford Health NHS Foundation Trust, Warneford Hospital, Warneford Lane, Oxford, OX3 7JX, UK.
  • Cairns I; Research and Development, Devon Partnerships NHS Foundation Trust, Wonford House, Dryden Road, Exeter, EX2 5AF, UK.
  • Dowling F; Cambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Coton House Level 6, Flat 61, Box 40, Hills Road, Cambridge, CB2 0QQ, UK.
  • Kabir T; The McPin Foundation, 7-14 Great Dover Street, London, SE1 4YR, UK.
  • Barnes TRE; Department of Medicine, The Centre for Psychiatry, Imperial College London, 7th Floor Commonwealth Building, Du Cane Road, London, W12 0NN, UK.
  • Lingford Hughes A; Centre for Psychiatry, Imperial College London, Burlington Danes, Hammersmith Campus Imperial College, London, UK.
  • Hosseini AA; Department of Neurology, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, NG7 2UH, UK.
  • Harrower T; Royal Devon and Exeter Hospital, Royal Devon and Exeter NHS Foundation Trust, Wonford, Barrack Road, Exeter, EX2 5DW, UK.
  • Buckley C; Nuffield Department of Clinical Neurosciences, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, West Wing, Headley Way, Oxford, OX3 9DU, UK.
  • Coles A; Department of Clinical Neurosciences, University of Cambridge, Box 165, Addenbrooke's Hospital, Cambridge, CB2 2QQ, UK. ajc1020@medschl.cam.ac.uk.
Trials ; 20(1): 331, 2019 Jun 07.
Article in En | MEDLINE | ID: mdl-31174586
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psychotic Disorders / Antipsychotic Agents / Immunoglobulins, Intravenous / Rituximab Type of study: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Trials Journal subject: MEDICINA / TERAPEUTICA Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psychotic Disorders / Antipsychotic Agents / Immunoglobulins, Intravenous / Rituximab Type of study: Clinical_trials / Diagnostic_studies / Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Trials Journal subject: MEDICINA / TERAPEUTICA Year: 2019 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom