Methotrexate in the Treatment of Idiopathic Granulomatous Mastitis.
J Rheumatol
; 47(6): 924-927, 2020 06 01.
Article
in En
| MEDLINE
| ID: mdl-31203215
ABSTRACT
OBJECTIVE:
Idiopathic granulomatous mastitis (IGM) is a disfiguring inflammatory breast disease without effective treatment. We report the largest IGM cohort treated with methotrexate (MTX) monotherapy.METHODS:
Chart review was performed on patients evaluated by the Stanford Immunology and Rheumatology Clinic, with histopathologically established IGM treated with MTX, and at least 1 followup appointment.RESULTS:
Nineteen female patients with a mean age of 33.5 years were identified. Most failed treatment with antibiotics, prednisone, and surgical intervention. By 15 months of treatment with MTX, 94% had disease improvement and 75% achieved disease remission.CONCLUSION:
MTX monotherapy is an effective treatment for IGM.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Methotrexate
/
Granulomatous Mastitis
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
J Rheumatol
Year:
2020
Document type:
Article
Affiliation country:
United States
Publication country:
CA
/
CANADA
/
CANADÁ