Your browser doesn't support javascript.
loading
Methotrexate in the Treatment of Idiopathic Granulomatous Mastitis.
Postolova, Anna; Troxell, Megan L; Wapnir, Irene L; Genovese, Mark C.
Affiliation
  • Postolova A; From the Division of Immunology and Rheumatology, Department of Pathology, Department of Surgery, Stanford University School of Medicine, Palo Alto, California, USA. postolov@stanford.edu.
  • Troxell ML; A. Postolova, MD, MPH, Fellow in Allergy/Immunology/Rheumatology, Division of Immunology and Rheumatology, Stanford University School of Medicine; M.L. Troxell, MD, PhD, Professor of Pathology, Stanford University Medical Center; I.L. Wapnir, MD, Professor of Surgery, Department of Surgery, Stanford
  • Wapnir IL; From the Division of Immunology and Rheumatology, Department of Pathology, Department of Surgery, Stanford University School of Medicine, Palo Alto, California, USA.
  • Genovese MC; A. Postolova, MD, MPH, Fellow in Allergy/Immunology/Rheumatology, Division of Immunology and Rheumatology, Stanford University School of Medicine; M.L. Troxell, MD, PhD, Professor of Pathology, Stanford University Medical Center; I.L. Wapnir, MD, Professor of Surgery, Department of Surgery, Stanford
J Rheumatol ; 47(6): 924-927, 2020 06 01.
Article in En | MEDLINE | ID: mdl-31203215
ABSTRACT

OBJECTIVE:

Idiopathic granulomatous mastitis (IGM) is a disfiguring inflammatory breast disease without effective treatment. We report the largest IGM cohort treated with methotrexate (MTX) monotherapy.

METHODS:

Chart review was performed on patients evaluated by the Stanford Immunology and Rheumatology Clinic, with histopathologically established IGM treated with MTX, and at least 1 followup appointment.

RESULTS:

Nineteen female patients with a mean age of 33.5 years were identified. Most failed treatment with antibiotics, prednisone, and surgical intervention. By 15 months of treatment with MTX, 94% had disease improvement and 75% achieved disease remission.

CONCLUSION:

MTX monotherapy is an effective treatment for IGM.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Methotrexate / Granulomatous Mastitis Limits: Adult / Female / Humans Language: En Journal: J Rheumatol Year: 2020 Document type: Article Affiliation country: United States Publication country: CA / CANADA / CANADÁ
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Methotrexate / Granulomatous Mastitis Limits: Adult / Female / Humans Language: En Journal: J Rheumatol Year: 2020 Document type: Article Affiliation country: United States Publication country: CA / CANADA / CANADÁ