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Estimation of influenza and respiratory syncytial virus hospitalizations using sentinel surveillance data-La Paz, Bolivia. 2012-2017.
Chavez, Dabeyva; Gonzales-Armayo, Vicente; Mendoza, Elvis; Palekar, Rakhee; Rivera, Rosario; Rodriguez, Angel; Salazar, Claudia; Veizaga, Angel; Añez, Arletta.
Affiliation
  • Chavez D; Minister of Health, La Paz, Bolivia.
  • Gonzales-Armayo V; Minister of Health, La Paz, Bolivia.
  • Mendoza E; Servicio Departamental de Salud, La Paz, Bolivia.
  • Palekar R; Pan American Health Organization, WDC, USA.
  • Rivera R; Instituto de Laboratorios en Salud INLASA, La Paz, Bolivia.
  • Rodriguez A; Pan American Health Organization, WDC, USA.
  • Salazar C; Servicio Departamental de Salud, La Paz, Bolivia.
  • Veizaga A; Hospital Boliviano Holandés, El Alto, Bolivia.
  • Añez A; Pan American Health Organization, La Paz, Bolivia.
Influenza Other Respir Viruses ; 13(5): 477-483, 2019 09.
Article in En | MEDLINE | ID: mdl-31206257
OBJECTIVE: The objective was to estimate the number of hospitalizations associated with influenza and RSV using data from severe acute respiratory infection (SARI) sentinel surveillance from El Alto-La Paz. Bolivia. METHODS: All persons who met the case definition for SARI at one sentinel hospital had a clinical sample collected and analyzed by rRT-PCR for influenza and by indirect immunofluorescence for RSV. The SARI-influenza and SARI-RSV case counts were stratified by six age groups. The proportion of cases captured in the sentinel hospital in relation to the non-sentinel hospitals of area was multiplied by the age-specific census population, to build the denominators. The annual incidence and a 95% confidence interval (CI) were estimated. RESULTS: During 2012-2017, n = 2606 SARI cases were reported (average incidence 120/100 000 inhabitants [95% CI: 116-124]); the average incidence of influenza-associated SARI hospitalization was 15.3/100 000 (95% CI: 14.1-16.7), and the average incidence of RSV-associated SARI hospitalization was 9/100 000 inhabitants (95% CI: 8.1-10.1). The highest incidence of influenza was among those less than one year of age (average 174.7/100 000 [range: 89.1-299.5]), followed by those one to four years of age (average 51.8/100 000 [range: 19.8-115.4]) and then those 65 years of age and older (average 47.7/100 000 [range: 18.8-117]). For RSV, the highest incidence was highest among those less than one year of age (231/100 000 [range: 119.9-322.9]). CONCLUSION: Influenza and RSV represent major causes of hospitalization in La Paz, Bolivia-with the highest burden among children under one year of age. Our estimates support current prevention strategies in this age group.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Syncytial Virus Infections / Sentinel Surveillance / Influenza, Human / Hospitalization Type of study: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Humans / Infant / Middle aged Country/Region as subject: America do sul / Bolivia Language: En Journal: Influenza Other Respir Viruses Journal subject: VIROLOGIA Year: 2019 Document type: Article Affiliation country: Bolivia Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Syncytial Virus Infections / Sentinel Surveillance / Influenza, Human / Hospitalization Type of study: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Humans / Infant / Middle aged Country/Region as subject: America do sul / Bolivia Language: En Journal: Influenza Other Respir Viruses Journal subject: VIROLOGIA Year: 2019 Document type: Article Affiliation country: Bolivia Country of publication: United kingdom