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Glutamine Antagonist JHU083 Normalizes Aberrant Glutamate Production and Cognitive Deficits in the EcoHIV Murine Model of HIV-Associated Neurocognitive Disorders.
Nedelcovych, Michael T; Kim, Boe-Hyun; Zhu, Xiaolei; Lovell, Lyndah E; Manning, Arena A; Kelschenbach, Jennifer; Hadas, Eran; Chao, Wei; Prchalová, Eva; Dash, Ranjeet P; Wu, Ying; Alt, Jesse; Thomas, Ajit G; Rais, Rana; Kamiya, Atsushi; Volsky, David J; Slusher, Barbara S.
Affiliation
  • Nedelcovych MT; Johns Hopkins Drug Discovery, 855 North Wolfe Street, Baltimore, MD, 21205, USA.
  • Kim BH; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Zhu X; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Lovell LE; Department of Medicine, Icahn School of Medicine at Mount Sinai, Annenberg Building Floor 21, Room 42, 1468 Madison Ave, New York, NY, 10029, USA.
  • Manning AA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Kelschenbach J; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Hadas E; Johns Hopkins Drug Discovery, 855 North Wolfe Street, Baltimore, MD, 21205, USA.
  • Chao W; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Prchalová E; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Dash RP; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Wu Y; Graduate Program in Neuroscience, University of Washington, Seattle, WA, USA.
  • Alt J; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Thomas AG; Department of Medicine, Icahn School of Medicine at Mount Sinai, Annenberg Building Floor 21, Room 42, 1468 Madison Ave, New York, NY, 10029, USA.
  • Rais R; Department of Medicine, Icahn School of Medicine at Mount Sinai, Annenberg Building Floor 21, Room 42, 1468 Madison Ave, New York, NY, 10029, USA.
  • Kamiya A; Department of Medicine, Icahn School of Medicine at Mount Sinai, Annenberg Building Floor 21, Room 42, 1468 Madison Ave, New York, NY, 10029, USA.
  • Volsky DJ; Johns Hopkins Drug Discovery, 855 North Wolfe Street, Baltimore, MD, 21205, USA.
  • Slusher BS; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
J Neuroimmune Pharmacol ; 14(3): 391-400, 2019 09.
Article in En | MEDLINE | ID: mdl-31209775
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azo Compounds / Caproates / Prodrugs / AIDS Dementia Complex / Cognition Disorders / Glutamates / Glutamine Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: J Neuroimmune Pharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / NEUROLOGIA Year: 2019 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azo Compounds / Caproates / Prodrugs / AIDS Dementia Complex / Cognition Disorders / Glutamates / Glutamine Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: J Neuroimmune Pharmacol Journal subject: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / NEUROLOGIA Year: 2019 Document type: Article Affiliation country: United States