Radiotherapy, Lymphopenia, and Host Immune Capacity in Glioblastoma: A Potentially Actionable Toxicity Associated With Reduced Efficacy of Radiotherapy.

Kleinberg, Lawrence; Sloan, Lindsey; Grossman, Stuart; Lim, Michael

Kleinberg, Lawrence; Sloan, Lindsey; Grossman, Stuart; Lim, Michael.

Affiliation

Kleinberg L; Department of Radiation Oncology and Radiation Molecular Sciences, Johns Hopkins University, Baltimore, Maryland.
Sloan L; Department of Radiation Oncology and Radiation Molecular Sciences, Johns Hopkins University, Baltimore, Maryland.
Grossman S; Department of Oncology, Johns Hopkins University, Baltimore, Maryland.
Lim M; Department of Neurosurgery, Johns Hopkins University, Baltimore, Maryland.

Neurosurgery ; 85(4): 441-453, 2019 10 01.

Article in En | MEDLINE | ID: mdl-31232425

Subject(s)

Brain Neoplasms/immunology; Brain Neoplasms/radiotherapy; Glioblastoma/immunology; Glioblastoma/radiotherapy; Lymphopenia/immunology; Radiotherapy/adverse effects; Brain Neoplasms/diagnosis; Glioblastoma/diagnosis; Humans; Immunity, Cellular/immunology; Immunity, Cellular/radiation effects; Lymphopenia/diagnosis; Lymphopenia/etiology; Radiotherapy/trends; Treatment Outcome

Key words

CD4 T cells; Glioblastoma; Immunity; Lymphopenia; Neoplasm; Radiotherapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiotherapy / Brain Neoplasms / Glioblastoma / Lymphopenia Type of study: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: Neurosurgery Year: 2019 Document type: Article Country of publication: United States

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