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Nrf2 drives oxidative stress-induced autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback loop to protect intervertebral disc from degeneration.
Tang, Zehan; Hu, Bo; Zang, Fazhi; Wang, Jianxi; Zhang, Xingda; Chen, Huajiang.
Affiliation
  • Tang Z; Department of Spinal Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
  • Hu B; Department of Spinal Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
  • Zang F; Department of Spinal Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
  • Wang J; Department of Spinal Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
  • Zhang X; Department of Spinal Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China.
  • Chen H; Department of Spinal Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China. spine.chen@163.com.
Cell Death Dis ; 10(7): 510, 2019 07 01.
Article in En | MEDLINE | ID: mdl-31263165
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-E2-Related Factor 2 / Intervertebral Disc Degeneration / Nucleus Pulposus / Kelch-Like ECH-Associated Protein 1 / Intervertebral Disc Type of study: Prognostic_studies Limits: Adult / Aged / Animals / Humans / Middle aged Language: En Journal: Cell Death Dis Year: 2019 Document type: Article Affiliation country: China Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-E2-Related Factor 2 / Intervertebral Disc Degeneration / Nucleus Pulposus / Kelch-Like ECH-Associated Protein 1 / Intervertebral Disc Type of study: Prognostic_studies Limits: Adult / Aged / Animals / Humans / Middle aged Language: En Journal: Cell Death Dis Year: 2019 Document type: Article Affiliation country: China Country of publication: United kingdom